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Target AQ-C18 chromatographic column

Time:2020-05-30 09:14Click:199
● the unique innovative design of the bonding stationary phase is adopted. The silica gel with high purity and good mechanical stability is used as the matrix. Through the use of high purity bonding reagent, Zui can realize the coverage of single functional group and the complete sealing of residual silicone alcohol base with a large limit, and the carbon content can be as high as 16.0%.
● by strictly controlling the formation of monolayer and the chemical reaction conditions of tail sealing, reliable reproducibility between columns can be ensured. The surface coverage has reached Zui maximization, so it has excellent stability. The filler is a uniform spherical particle with an aperture of 120 μ m or 200 μ m and a specific surface area of 310m2 / g or 200m2 / g.
● the target aq-c18 column bed density obtained by filling with unique homogenate filling technology is uniform and stable, so it can ensure high column efficiency of Zui.
● Target aq-c18 is specially designed for the separation of polar and hydrophilic compounds, with strong retention effect and good selectivity. The patented surface modification will not cause the breakdown of C18 bonding phase in pure water, showing excellent separation performance.
● pure water can be used as mobile phase in the range of pH2 ~ 8.5. It is suitable for the separation of acid, neutral and basic compounds, as well as many drugs, polypeptides, etc

Chromatographic conditions of amoxicillin detection pattern:

Column:

Target  AQ-C18   5 µm, 4.6 × 150 mm

Mobile phase:

0.05 mol/L KH2PO4 (adjust pH to 5.0 with 2 mol

/L KOH) : ACN = 97.5 : 2.5 (v/v)

Flow rate:

1.0 mL/min

Temperature:

25 oC

Detection:

UV 254 nm

Injection volume:

20 µL

Sample:

Amoxicillin (Amoxicillin)


Chromatographic conditions of sugar and organic acid: 

Column:

Target  AQ-C18  ( 5 µm, 120 Å, 4.6 x 250 mm )

Mobile phase:

0.1M Sodium dihydrogen phosphate ( pH 3.1 by H3PO4 )

Flow rate:

1mL/min

Temperature:

25 ℃

Detection:

RI(35  ℃)

Injection volume:

20 µL

Sample:

mixed sample

 


Organic acid chromatographic conditions: 

Column:

Target AQ-C18  5µm, 4.6 ×150 mm

Mobile phase:

0.10 M Phosphate buffer, pH 3.1

Flow rate:

1.0 mL/min

Temperature:

23 oC

Detection:

UV 210 nm

Injection volume:

5 µL

Sample:

1. Formic Acid(蚁酸,10 mM), 2. Malic Acid(苹果酸, 10 mM), 3. Lactic Acid(乳酸,10 mM), 4. Acetic Acid(乙酸, 10 mM), 5. Citric Acid(柠檬酸, 10 mM), 
6. Succinic Acid(琥珀酸,10 mM)


Target AQ-C18 Product specification:

name

Particle size

Specifications

Article No

Target AQ-C18

3μm

3.0mm×100mm

311833-3010

Target AQ-C18

3μm

4.6mm×100mm

311833-4610

Target AQ-C18

4μm

4.6mm×150mm

311834-4615

Target AQ-C18

5μm

2.1mm×30mm

311845-2103

Target AQ-C18

5μm

2.1mm×50mm

311845-2105

Target AQ-C18

5μm

2.1mm×100mm

311845-2110

Target AQ-C18

5μm

3.0mm×30mm

311845-3003

Target AQ-C18

5μm

3.0mm×50mm

311845-3005

Target AQ-C18

5μm

3.0mm×100mm

311845-3010

Target AQ-C18

5μm

4.6mm×30mm

311845-4603

Target AQ-C18

5μm

4.6mm×50mm

311845-4605

Target AQ-C18

5μm

4.6mm×100mm

311845-4610

Target AQ-C18

5μm

4.6mm×150mm

311845-4615

Target AQ-C18

5μm

4.6mm×250mm

311845-4625

Target AQ-C18

5μm

4.6mm×300mm

311845-4630

Target AQ-C18

5μm

10.0mm×50mm

311845-10005

Target AQ-C18

5μm

10.0mm×100mm

311845-10010

Target AQ-C18

5μm

21.2mm×50mm

311845-21205

Target AQ-C18

5μm

21.2mm×100mm

311845-21210

Target AQ-C18

5μm

30.0mm×50mm

311845-30005

Target AQ-C18

5μm

30.0mm×100mm

311845-30010

Target AQ-C18

5μm

50.0mm×50mm

311845-50005

Target AQ-C18

5μm

50.0mm×250mm

311845-50025

Target AQ-C18

10μm

10.0mm×50mm

311849-10005

Target AQ-C18

10μm

10.0mm×100mm

311849-10010

Target AQ-C18

10μm

21.2mm×50mm

311849-21205

Target AQ-C18

10μm

21.2mm×100mm

311849-21210

Target AQ-C18

10μm

30.0mm×50mm

311849-30005

Target AQ-C18

10μm

30.0mm×100mm

311849-30010

Target AQ-C18

10μm

50.0mm×50mm

311849-50005

Target AQ-C18

10μm

50.0mm×250mm

311849-50025

● test samples of some traditional Chinese medicine: amoxicillin, cyclic adenosine for injection, valsartan, vitamin B12, toxamine, thiamethoxam, chloroammonia, caffeine, Jinggangmycin, nucleotide, benzoic acid preservative, sodium orthohydroxymandelate, Rehmannia glutinosa (Catalpol), phloroglucinol, Anemarrhena (mangiferin), saccharin, acesulfame, gentamicin, vancomycin Benzoic acid, sorbic acid, carmine, vitamin B6, gentiopicroside
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