MS chiral series of high performance chiral chromatographic
MS chiral system high performance chiral chromatographic column is developed and produced by many senior experts in Germany
MS chiral series chiral columns can replace Daicel's mainstream chiral columns perfectly. In China, Chengdu Moore Scientific Instrument Co., Ltd. is the sole agent for sales and technical services. The laboratory established by Chengdu Moore company can also screen suitable chiral columns and provide sample preparation and purification services for new chiral compounds synthesized by customers.
Chiral column stationary phase
1、 Packing type
| Brush type or prikle type | Serotype |
| Polysaccharide derivative | Coordination exchange type |
| Cyclodextrin | Crown ethers type |
| Macrocyclic antibiotic | Other special columns |
2、 Classification of stationary phase
1. Polysaccharide derivatives
| model | Functional group (stationary phase) | Practical application of some samples (please contact the sales representative for Atlas and more applications) |
| MS-OD |
Cellulose - III (3,5dimethylphenyl carbamate) |
Benzoin, valsartan, imidazoline, metolachlor, 2 - (4-methoxyphenoxy) propionate, lansoprazole, 2-bromo-1 - (4-methoxy) ethanol, agliptin, tamsulosin hydrochloride, eprazole, oxaliplatin, fmoc-l-alanine, fmoc-o-tert-butyric acid-l-glutamine, fmoc-l-phenylalanine, n-fluorenylmethoxycarbonyl-n-triphenyl-histidine, n-alpha-fmoc-n-epsilon- Tert oxocarbonyl lysine, fluorenylmethoxycarbonyl methionine, fmoc-o-tert-butyl-l-serine, fmoc-o-tert-butyl-l-threonine, fmoc-l-valine, n-alpha-fluorenylmethoxycarbonyl-n-in-tert-butoxycarbonyl-tryptophan, propranolol, alanine, viggliptin, metalaxyl, stilbestine hydrochloride, methionine, naphthalene ethanol, warfarin, intermediate of linagliptin, naphthylamine, spermiopropyridine Metolachlor, indoxacarb, Fmoc Arg (PH) - Oh, sitafloxacin, duloxetine naphthalene ether oxalate, fmoc-o-tert-butyl-l-tyrosine, avanafil, duloxetine hydrochloride, (3R, 3R) - N, 4-dimethyl-1-benzyl-3-piperidine hydrochloride, L / D-cysteine, (r1r) - 1, 2-cyclohexanedicarboxylic acid, lorocarcillin hydrochloride, paroxetine, enol silyl ether, chlorocaiserin hydrochloride, methionine, phenylethanol, diphenylproline, alkaloids, ofloxacin, atropine, Nateglinide impurity B, dapoxetine hydrochloride, cysteine, argatroban, levofloxacin, diazepam, diazepam Quinolines, L-1 (benzene with seven membered cyclotrifluoroacetyl group), naphthalimide, toluene ester, ether, valsartan, cysteine, (-) - N, n-dimethyl-d-mandelamide, metoprolol tartrate, iridium complex,,, fmoc-d / L-His (TRP), fmoc-d / L-Ala, fmoc-d / L-Trp, fmoc-d / L-Phe, mirtazapine, n-cbz-dl-valine, flavanone, methyl mandelate, mexole BAMO |
| MS-OJ |
Cellulose - III (4methylbenzoate) |
CIS bifenthrin, piroprofen, ibuprofen, dextran rich permethrin, flumequine, folidazole, 2-methyl-6-butylenaphthalene, thiophenol, (1-hydroxyethyl) ferrocene, manidipine hydrochloride racemate, clopidogrel bisulfate, flurbiprofen, methyl flurbiprofen, propiconazole, diflubenzoate, fumaric acid / dichloric acid, vitamin C, manidipine hydrochloride, flavonoids Carbonic anhydride, oxazolidinones, nimodipine, tert butylsulfonamide, lineidomide, averbatan sodium, toluene esters, biphenyl esters, polycyclic aromatic hydrocarbons, benzene rings, paroxetine hydrochloride, glycosides, lenalidomide, etc |
| MS=AD | Amylose Tris [(s) - α-Methyl phenyl carbamate) | Repaglinide, boc-d-phenylalanine, cbz-l-valine, dihydrosalicylomycin, tetrahydrophthalic acid, r-9 - (2-hydroxypropyl) adenine, levodropropizine, paroxamide, terbutaline, acetoin, (3 ', 4 '- dioxyphenyl) - 2-amino-2-methoxypropionitrile, gossypol, lignan, Nateglinide, nitrendipine, Cyclohexanediamine tartrate, DL panthenol, fatty acid derivatives, yp001 organic acids, Fmoc - (2R, 3R) - thr - (s) - procooh, esomeprazole, berberine, dl-5-benzylhydantoin, methylenediamide, glinide, toluenone, biphenylketone, trifluoromethyl benzophenone, levetiracetam and dextrocetam, D / L malondiamine tartrate, atorvastatin calcium, propranolol, benzoin ether (ethoxybenzoin) |
| MS-AS |
Amylose - 3 (3,5dimethylphenyl carbamate) |
L / d-pyroglutamic acid, naproxen, naproxen methyl ester, acyl topril, metoprolol, terpenes, methylenecycloamides, R - (-) - 3-aminopiperidine dihydrochloride, steroids, aprost, α - tetrahydronaphthol |
| MS-OZ |
Cellulose - III (3-chloro-4-methylphenyl carbamate) |
Praziquantel, trimebutine, 1,1 '- bi-2-naphthol |
| MS-AY |
Amylose - 3 (5-chloro-2-methylphenyl carbamate) |
N-acetyl-dl-tyrosine, rivaroxaban, s-3-cyclohexenoic acid, ezetimibe, carvedilol, 1-phenyl-1-hexanol, 1-phenyl-1-pentanol, benzoic acid (2-heptanol) ester, salbutamol, alkaloids ... |
| MS-OX |
Cellulose - III (4-chloro-3-methylphenyl carbamate) |
The results showed that tert butoxycarbonyl - (3R) - 3-aminopiperidine, methadone, salbutamol, oxiracetam, engelgen, 6-chloro-2-hydroxynicotinic acid, fmoc-d-3-pal-oh protective amino acids, alapril, furanbenzoic acid, argatroban, etc |
| MS-IB |
Covalent bonding Cellulose tris (3,5-dimethylphenyl carbamate) |
Levosimendan, atenolol, warfarin |
| MS-IC |
Covalent bonding Cellulose tris (3,5-dichlorophenyl carbamate) |
Fmoc-l-leucine, fmoc-n-triphenylmethyl-l-asparagine, fmoc-l-proline, zopiclone, proline, DL phenylalanine, iridium complexes, pr |
3. Proteins
| Chiral column model | Functional group (stationary phase) | Practical application of some samples (please contact the sales representative for Atlas and more applications) |
| MS-BSA | Serum proteins | Methotrexate, pidotimod, calcium methyltetrahydrofolate, tryptophan, tartrate, ornidazole phosphate disodium, tertiazolamide phosphate, oxazolidinone antibacterial agents, etc |
Some sample analysis applications
More and more considerate services
1、 Chiral column screening service
The chromatographic system can be equipped with 6 chromatographic columns for screening
Automatic switching system of chromatographic column is adopted
Mobile phase automatic switching system and multiple detectors are used to adapt to different samples
Results within 5 days
2、 Preparation and purification of chiral samples
Specification and model of chiral column
| MS-Chiral column model | Filler name | Particle size |
Specification of chiral column (length * inner diameter) |
| MS-OD | Cellulose tris (3,5-dimethylphenyl carbamate) | 3um、5um、10um、20um |
(50/100/150/250)*4.6mm 250*(20/30/50)mm |
| MS-AD | Amylose Tris [(s) - α - methylphenyl carbamate) | 3um、5um、10um、20um |
(50/100/150/250)*4.6mm 250*(20/30/50)mm |
| MS-OJ | Cellulose tris (4-methylbenzoate) | 3um、5um、10um、20um |
(50/100/150/250)*4.6mm 250*(20/30/50)mm |
| MS-AS | Amylose tris (3,5-dimethylphenyl carbamate) | 3um、5um、10um、20um |
(50/100/150/250)*4.6mm 250*(20/30/50)mm |
| MS-OZ | Cellulose tris (3-chloro-4-methylphenyl carbamate) | 3um、5um、10um、20um |
(50/100/150/250)*4.6mm 250*(20/30/50)mm |
| MS-AY | Amylose tris (5-chloro-2-methylphenyl carbamate) | 3um、5um、10um、20um |
(50/100/150/250)*4.6mm 250*(20/30/50)mm |
| MS-OX | Cellulose tris (4-chloro-3-methylphenyl carbamate) | 3um、5um、10um、20um |
(50/100/150/250)*4.6mm 250*(20/30/50)mm |
| MS-IB | Covalently bonded cellulose tris (3,5-dimethylphenyl carbamate) | 5um、10um |
(50/100/150/250)*4.6mm 250*(20/30/50)mm |
| MS-IC | Covalently bonded cellulose tris (3,5-dichlorophenyl carbamate) | 5um、10um |
(50/100/150/250)*4.6mm 250*(20/30/50)mm |
| MS-1 | Single bonded cyclodextrin tris (4-chlorophenyl carbamate) | 5um、10um | (50/100/150/250)*4.6mm |
| MS-2 | Single bonded cyclodextrin tris (3,5-dimethylphenyl carbamate) | 5um、10um | (50/100/150/250)*4.6mm |
| MS-3 | Multibonded cyclodextrin tris (4-chlorophenyl carbamate) | 5um、10um | (50/100/150/250)*4.6mm |
| MS-4 | Multibonded cyclodextrin tris (3,5-dimethylphenyl carbamate) | 5um、10um | (50/100/150/250)*4.6mm |
| MS-BSA | Bovine serum protein | 5um、10um | (50/100/150/250)*4.6mm |
